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FlexiVent® system

FlexiVent ®系统

公司名称: SCIREQ Scientific Respiratory Equipment
产品编号: FV-M1
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Measurement of Airway Responsiveness in the Anesthetized Mouse
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2013-04-05
[Abstract]  Airway hyperresponsiveness to methacholine is an important characteristic of asthma. Many devices can be used to measure airway responsiveness in the mouse but it is well established that the invasiveness of a measurement technique is correlated with its precision and reproducibility. This protocol describes how to measure airway responses to aerosolized methacholine in anesthetized, tracheotomized, and mechanically ventilated mice using the forced oscillation technique with FlexiVent® (SCIREQ). This is a computer-controlled precision piston pump that can intersperse mechanical ... [摘要]  气道对乙酰甲胆碱的高反应性是哮喘的一个重要特征。 许多装置可以用于测量小鼠中的气道反应性,但是已经确定的是,测量技术的侵入性与其精确度和再现性相关。 该协议描述了如何使用强制振荡技术用FlexiVent </sup>(SCIREQ)测量在麻醉,气管切开和机械通气的小鼠中气雾化的乙酰甲胆碱的气道反应。 这是一个计算机控制的精密活塞泵,可以穿插机械通气与体积和压力控制操作,以获得准确,可重复的呼吸力学测量。

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