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N,N-Dimethylformamide

N,N-二甲基甲酰胺

公司名称: EMD Millipore
产品编号: 103053
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IFN-α Inhibition Assay in vitro
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2013-06-20
[Abstract]  During viral infections Interferon-α (IFN-α) is expressed by infected host cells. IFN-α binds to its receptor (IFNAR1/2), which leads to the activation of downstream signaling via JAK-STAT. This signaling cascade results in the expression of several hundred different genes, so called interferon-stimulated gene, which lead to an antiviral state of the infected and the neighboring cells. [摘要]  在病毒感染期间,干扰素-α(IFN-α)由感染的宿主细胞表达。 IFN-α结合其受体(IFNAR1/2),其导致通过JAK-STAT的下游信号传导的激活。 这种信号级联导致数百种不同基因的表达,所谓的干扰素刺激基因,其导致感染细胞和相邻细胞的抗病毒状态。

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