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29 G x 1cc BDTM self-contained U100 (Asia/Pacific)

29 G x 1cc BDTM self-contained U100 (Asia/Pacific)

公司名称: BD
产品编号: 320310
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Serial Transfer of Human Hematopoietic and Hepatic Stem/progenitor Cells
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2013-12-05
[Abstract]  A range of assays have been developed to determine the stemness or stem cell activity of human stem cells. The key assays of stem cells are functional: they must show self-renewal and the ability to generate the appropriate tissue. The best assays available to study this property in putative human stem cells involve xeno-transplantation into immune-deficient mice. Demonstration of both long-term (2-3 months) multi-lineage reconstitution of human blood or liver in a murine host and the ability of the putative stem cells to mediate reconstitution of a secondary host upon re-isolation from the ... [摘要]  已经开发了一系列测定来确定人类干细胞的干细胞或干细胞活性。 干细胞的关键测定是功能性的:它们必须显示自我更新和产生适当组织的能力。 用于在推定的人类干细胞中研究该特性的最佳测定涉及到免疫缺陷小鼠的异种移植。 在鼠宿主中长期(2-3个月)多谱系重建人血液或肝脏以及当从初级小鼠再分离时推定干细胞介导次级宿主重建的能力一般 被接受为证明人造血干细胞和肝干细胞存在的金标准。 在这里,我们描述了用来自人胎儿肝脏的CD34 +干细胞重建NOD-scid IL-2Rγ(NSG)小鼠的方法和CD34 + 细胞进行连续移植。

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