{{'Search' | translate}}
 

C3A [HepG2/C3A, derivative of Hep G2 (ATCC HB-8065)]

C3A [HepG2 / C3A,Hep G2的衍生物(ATCC HB-8065)]

公司名称: ATCC
产品编号: CRL-10741TM
Bio-protocol()
Company-protocol()
Other protocol()

Infectious Virus Yield Assay for Hepatitis E Virus
Author:
Date:
2014-08-05
[Abstract]  Hepatitis E virus (HEV) is one of the main causes of acute hepatitis worldwide. Infections are particularly severe in pregnant women and chronic hepatitis E is known to occur in immunocompromised patients. Current therapy (ribavirin or pegylated alpha interferon) has severe side effects and cannot be employed in all patients. In order to evaluate potential new inhibitors of HEV replication, a virus yield assay can be employed in which the amount of viral RNA progeny released into the culture medium is quantified by reverse-transcription quantitative PCR (RT-qPCR) (Debing et al., ... [摘要]  戊型肝炎病毒(HEV)是全世界急性肝炎的主要原因之一。 感染在孕妇中特别严重,已知慢性戊型肝炎发生在免疫受损的患者中。 目前的治疗(利巴韦林或聚乙二醇化α干扰素)具有严重的副作用,不能用于所有患者。 为了评估潜在的新的HEV复制抑制剂,可以使用病毒产量测定法,其中释放到培养基中的病毒RNA子代的量通过逆转录定量PCR(RT-qPCR)(Debing等人, al 。,2014)。

产品评论