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公司名称: USA Scientific
产品编号: 1111-0000
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Preparation and Immunofluorescence Staining of the Trachea in Drosophila Larvae and Pupae
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2016-05-05
[Abstract]  The Drosophila melanogaster trachea is a branched network of rigid chitin-lined tubes that ramify throughout the body and functions as the fly’s respiratory organ. Small openings at the ends of the tracheal tubes allow gas exchange to occur by diffusion between internal tissues and the exterior environment. Tracheal tubes are lined by a single layer of epithelial cells, which secrete chitin and control tube morphology and size. Studies of tracheal development in Drosophila embryos have elucidated fundamental mechanisms of tube morphogenesis and ... [摘要]   melanogaster 气管是一种由几丁质内衬的管组成的分支网络,分布在整个身体并作为苍蝇的呼吸器官。气管管端部的小开口允许通过内部组织和外部环境之间的扩散而发生气体交换。气管管由单层上皮细胞衬里,其分泌几丁质和对照管形态和尺寸。在Drosop hila 胚胎中的气管发育的研究阐明了管形态发生和维持体内的基本机制,并且鉴定了调节这些过程的主要信号传导途径(Manning和Krasnow,1993; Affolter和Shilo,2000; Zuo等人,2013; Kerman等人,2006; Schottenfeld等人, em,2010)。近年来,在变态过程中对气管的兴趣日益增长,当在幼虫中用作呼吸器官的气管分支被修复或被由致动的气管祖细胞产生的新的气管组织或成熟的气管细胞(Manning和Krasnow,1993; Sato和Kornberg,2002; Guha等人,2008; Guha和Kornberg,2005; Weaver和Krasnow,2008; Pitsouli和Perrimon, 2010; Chen和Krasnow,2014)在过程结束时形成成人气管。正在进行的衰变和组织形成模拟其他生物体中组织修复和再生的方面,并且已经用于理解祖细胞如何分裂和分化(Pitsouli和Perrimon,2010; ...

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