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Refrigerated Tabletop Centrifuge for 50 ml conical tubes

冷冻台式离心机用于50ml锥形管

公司名称: Thermo Fisher Scientific
产品编号: 031220F
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Differentiation of Human Embryonic Stem Cells into Cone Photoreceptors
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2016-07-20
[Abstract]  Photoreceptors are specialized retinal neurons able to respond to light in order to generate visual information. Among photoreceptors, cones are involved in colors discrimination and high-resolution central vision and are selectively depleted in macular degenerations and cone dystrophies. A possible therapeutic solution for these disorders is to replace degenerating cells with functional cones. Here, we describe a simple protocol for the rapid production of large amount of cone photoreceptors from human pluripotent stem cells. The differentiation protocol is based on the “default pathway” of ... [摘要]  光感受器是能够响应光以产生视觉信息的专门的视网膜神经元。 在光感受器中,视锥细胞参与颜色辨别和高分辨率中心视觉,并且选择性缺失黄斑变性和视锥营养不良。 这些疾病的可能的治疗溶液是用功能性锥体代替变性细胞。 在这里,我们描述了一个简单的协议,从人类多能干细胞快速生产大量的锥形感光细胞。 分化方案基于使用BMP,TGFβ和WNT拮抗剂COCO的神经诱导的"默认途径"。

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