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Sonic dismembrator

声波解密器

公司名称: Thermo Fisher Scientific
产品编号: 100
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Activation of ER-regulated Fusion Proteins In Vivo
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2011-12-20
[Abstract]  Regulatable protein fusions can be made by attaching the hormone binding domain of the estrogen receptor to the N or C-terminus of a protein of interest. Activation of such ER-fusion proteins in vivo can be achieved by daily administration of a synthetic ligand, 4-hydroxytamoxifen (4OHT), via intraperitoneal (i.p.) injection. [摘要]  可调节的蛋白融合可以通过贴附雌激素受体的激素结合区域到所感兴趣的蛋白的N或C末端来制备。在生物体内的这种ER-融合蛋白的活化可以每天通过腹腔内注射一种合成的配体物质 4-羟基它莫西芬来完成。

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