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Lemongrass essential oil

公司名称: Merck
产品编号: 5521501
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Candida Biofilm Formation Assay on Essential Oil Coated Silicone Rubber
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Date:
2021-03-05
[Abstract]  

Development of biofilm associated candidemia for patients with implanted biomaterials causes an urgency to develop antimicrobial and biofilm inhibitive coatings in the management of recalcitrant Candida infections. Recently, there is an increase in the number of patients with biofilm formation and resistance to antifungal therapy. Therefore, there is a growing interest to use essential oils as coating agents in order to prevent biomaterial-associated Candida infections. Often high costs, complicated and laborious technologies are used for both applying the coating and determination of the

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[摘要]  [摘要]对于植入了生物材料的患者,与生物膜相关的念珠菌血症的发展导致迫切需要开发抗微生物和生物膜抑制性涂层,以应对顽固的念珠菌感染。近来,具有生物膜形成和抗真菌治疗抗性的患者数量增加。因此,有越来越多的兴趣使用精油作为涂层剂以防止生物材料-相关念珠菌感染。通常,高成本,复杂且费力的技术既用于涂覆涂层,又用于确定抗生物膜作用,这妨碍了对精油的快速筛选。为了更轻松,更便宜,更快速地确定精油涂层表面上念珠菌的生物膜形成,我们使用羟丙甲纤维素软膏/精油混合物开发了精油(柠檬皮油)涂层表面(硅橡胶)。此外,我们修改了“结晶紫结合法”以定量在柠檬草油涂层的硅橡胶表面上形成的念珠菌生物膜的生物膜质量。硅橡胶上的精油涂层和生物膜的生物量测定可通过简单且易于接近的设备轻松进行,因此,即使将特定的精油用作涂层剂,也将提供有关特定精油是否具有防腐性的快速信息。


[背景技术[ 0002 ...

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